Tropic Of Cancer Festival brings together 64 artists for a five-day celebration of rock, americana, soul, funk, and R&B music in Todo Santos, Mexico from January 14-18, 2026. The festival lineup features headliners La Santa Cecilia, Lettuce, Andy Frasco & the U.N., and Fruition, alongside notable acts including John Craigie, The Mother Hips, Break Science, and Mark Bryan. With a diverse mix of established and emerging artists spanning multiple genres, this standalone festival offers an extensive musical experience for fans of contemporary American roots music and funk. The event showcases both US-based acts and local Mexican talent, creating a unique cross-cultural musical celebration.